Indo-Scythians is a term used to refer to Scythians (Sakas), who migrated into parts of central and northern South Asia (Sogdiana, Bactria, Arachosia, Gandhara, Sindh, Kashmir, Punjab, Haryana, Rajasthan, UP and Bihar.), from the middle of the 2nd century BC to the 4th century AD.
The first Saka king in south Asia was Maues (Moga) (1st century BC) who established Saka power in Gandhara (modern day Pakistan and Afghanistan region) and gradually extended supremacy over north-western India. Indo-Scythian rule in northwestern India ended with the last Western Satrap Rudrasimha III in AD 395 who was defeated by the Indian Emperor Chandragupta II of the Gupta Empire. The power of the Saka rulers started to decline in the 2nd century AD after the Indo-Scythians were defeated by the south Indian Emperor Gautamiputra Satakarni of the Satavahana dynasty. Later the Saka kingdom was completely destroyed by Chandragupta II of the Gupta Empire in the 4th century.